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Learn about clinical pharmacology for the drug Seroquel (Quetiapine Fumarate). Find patient medical information for Seroquel oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Page 1 of 4 - Tips for tapering off Seroquel (quetiapine) - posted in Tapering: Administrators note: Please read further down in this topic for details ... Seroquel is an atypical antipsychotic for treatment of depressive episodes and acute manic episodes in bipolar disorder and is used to treat schizophrenia.